penetrance - Methods for Penetrance Estimation in Family-Based Studies

Implements statistical methods for estimating disease penetrance in family-based studies. Penetrance refers to the probability of disease manifestation in individuals carrying specific genetic variants. The package provides tools for age-specific penetrance estimation, handling missing data, and accounting for ascertainment bias in family studies. Cite as: Kubista, N., Braun, D. & Parmigiani, G. (2025) <doi:10.1093/bioadv/vbaf154>.